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LIMS1
Loading...Anti-LIMS1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Mouse Anti-LIMS1 Recombinant Antibody (clone 5G7B9) (VS3-XY1012)
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- Type: Mouse IgG1
- Application: ICC, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, ICC, IF
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC
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- Mouse Anti-LIMS1 Monoclonal Antibody (VS7-0425-WR299) (VS7-0425-WR299)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IF, ICC, FC, ELISA
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- Mouse Anti-LIMS1 Monoclonal Antibody (clone 5G7) (VS7-0425-WR615)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ICC, FC
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For Research Use Only. Not For Clinical Use.
Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Macrophages, Glandular and luminal cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HMC-1)
Interaction
Interacts (via LIM zinc-binding 5) with TGFB1I1 (By similarity). Interacts with integrin-linked protein kinase 1 (ILK) via the first LIM domain, and in competition with LIMS2. Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA. Interacts with SH3/SH2 adapter NCK2, thereby linking the complex to cell surface receptors.
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