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LRRC15

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For Research Use Only. Not For Clinical Use.


Background

Enables several functions, including fibronectin binding activity; laminin binding activity; and protein sequestering activity. Involved in several processes, including negative regulation of protein localization to plasma membrane; negative regulation of viral entry into host cell; and receptor-mediated virion attachment to host cell. Located in collagen-containing extracellular matrix and plasma membrane. Is active in apical plasma membrane.
Protein class

Plasma proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Langerhans cells, Fibroblasts, Basal keratinocytes, Hepatic stellate cells, Suprabasal keratinocytes, Endothelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (fHDF/TERT166, U-87 MG)

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