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LY6E
Lymphocyte antigen 6E is a protein that in humans is encoded by the LY6E gene. Increased expression of Ly6E is associated with poor survival outcome in multiple malignancies as determined by a survey of more than 130 published clinical studies of gene expression studies on cancer tissue samples and adjacent normal tissues. Ly6E is associated with drug resistance and tumor immune escape in breast cancer. Further research is required to validate Ly6E for translation research.
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Cytotrophoblasts, Granulosa cells)
Immune cell specificity
Immune cell enhanced (non-classical monocyte)
Cell line specificity
Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, MCF7)
Interaction
Interacts with CHRNA4.
More Types Infomation
- Recombinant Anti-human LY6E Antibody scFv Fragment (MOB-636-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, FC, FuncS
- Recombinant Anti-human LY6E Antibody Fab Fragment (MOB-636-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: Neut, IF, FuncS
- Recombinant Anti-human LY6E Antibody (MOB-636)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, FuncS
- Recombinant Human Anti-human LY6E Antibody scFv Fragment (MHH-636-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: Neut, WB, FuncS
- Rabbit Anti-LY6E polyclonal Antibody (MOB-0343MC)
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- Species Reactivity: Human
- Application: IF/ICC, ELISA
- Rabbit Anti-Human LY6E polyclonal Antibody (MOB-0315MC)
-
- Species Reactivity: Human, Mouse, Rat
- Application: WB
- Recombinant Human Anti-human LY6E Antibody Fab Fragment (MHH-636-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: IF, FuncS
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FuncS
- Human Anti-LY6E Recombinant Antibody; Fab Fragment (HPAB-N0169-YC-F(E)) (HPAB-N0169-YC-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FuncS
- Human Anti-LY6E Recombinant Antibody; scFv Fragment (HPAB-AP382-YC-S(P)) (HPAB-AP382-YC-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FuncS
- Human Anti-LY6E Recombinant Antibody; scFv Fragment (HPAB-N0169-YC-S(P)) (HPAB-N0169-YC-S(P))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FuncS
- Human Anti-Ly6E Recombinant Antibody; Fab Fragment (HPAB-0482-FY-F(E)) (HPAB-0482-FY-F(E))
-
- Species Reactivity: Pan troglodytes, Mouse
- Type: Human Fab, κ
- Application: RIA
- Mouse Anti-LY6E Recombinant Antibody; scFv Fragment (HPAB-AP383-YC-S(P)) (HPAB-AP383-YC-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: FuncS
- Human Anti-Ly6E Recombinant Antibody; scFv Fragment (HPAB-0482-FY-S(P)) (HPAB-0482-FY-S(P))
-
- Species Reactivity: Pan troglodytes, Mouse
- Type: Human scFv
- Application: RIA
- Mouse Anti-LY6E Recombinant Antibody; Fab Fragment (HPAB-AP383-YC-F(E)) (HPAB-AP383-YC-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: FuncS
- Human Anti-LY6E Recombinant Antibody; Fab Fragment (HPAB-AP382-YC-F(E)) (HPAB-AP382-YC-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FuncS
- Human Anti-LY6E Recombinant Antibody (HPAB-AP382-YC) (HPAB-AP382-YC)
-
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: FuncS
- Human Anti-LY6E Recombinant Antibody (HPAB-N0169-YC) (HPAB-N0169-YC)
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: FuncS
- Anti-LY6E-MC-vc-PAB-MMAE ADC (ADC-359CL)
-
- Target: LY6E
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-Human LY6E Recombinant Antibody (TAB-506CL)
-
- Species Reactivity: Human
- Type: Antibody
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For Research Use Only. Not For Clinical Use.