Intracellular, Membrane (different isoforms)
Cell type enhanced (Club cells, Cardiomyocytes, Excitatory neurons, Basal respiratory cells, Hepatocytes)
Group enriched (non-classical monocyte, intermediate monocyte)
Cell line enhanced (BJ, fHDF/TERT166, GAMG, HHSteC, HSkMC, OE19)
Interacts with nAChRs containing alpha-4:beta-2 (CHRNA4:CHRNB2) and alpha-7 (CHRNA7) subunits. Interacts with CHRNA4 probably in the endoplasmic reticulum prior to nAChR pentameric assembly (By similarity).
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For Research Use Only. Not For Clinical Use.