Lewis X

Trimeric-Lewis x; trimeric Lewis X

Sialyl lewis X(Slex) is a common sugar ligand in the family of selectin. By competitively binding with selectin to inflammatory cells, the inflammatory response can be inhibited. The occurrence of dairy cow mastitis from select element (Selectin) mediated inflammatory cells in the mammary gland large accumulation and overflow, and saliva acidification Louis X (sialyl lewis X, Slex) is one of the important moleculars that cause inflammation-select the minimum common sugar ligand, and it can serve as a kind of antigen, sugar and choose competitive mix of inflammatory cells, thus inhibiting the inflammatory response, and then achieve the goal of treatment of mastitis. Since Slex ACTS on selectin rather than pathogenic microorganisms, Slex can be used as a routine vaccine for the treatment of mastitis in cows. The key enzymes of Slex biosynthesis can be expressed by genetic engineering cloning and biosynthesis in vitro.