Disease related genes, Enzymes, Metabolic proteins, Potential drug targets
Intracellular
Cell type enhanced (Erythroid cells)
Low immune cell specificity
Low cell line specificity
Component of a signaling complex containing at least AKAP13, PKN1, MAPK14, ZAK and MAP2K3. Within this complex, AKAP13 interacts directly with PKN1, which in turn recruits MAPK14, MAP2K3 and ZAK (PubMed:21224381). Binds to DYRK1B/MIRK and increases its kinase activity (PubMed:11980910). Part of a complex with MAP3K3, RAC1 and CCM2 (By similarity). Interacts with ARRB1 (PubMed:16709866). (Microbial infection) Interacts with Yersinia YopJ.
Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase
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For Research Use Only. Not For Clinical Use.