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MIC
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- Mouse Anti-MIC Recombinant Antibody (HPAB-N0369-YC) (HPAB-N0369-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
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- Human Anti-MIC Recombinant Antibody (HPAB-N0368-YC) (HPAB-N0368-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, FuncS
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- Mouse Anti-MIC Recombinant Antibody (HPAB-N0367-YC) (HPAB-N0367-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib, FuncS
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- Mouse Anti-MIC Recombinant Antibody; scFv Fragment (HPAB-N0369-YC-S(P)) (HPAB-N0369-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Inhib
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- Human Anti-MIC Recombinant Antibody; scFv Fragment (HPAB-N0368-YC-S(P)) (HPAB-N0368-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Inhib, FuncS
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- Mouse Anti-MIC Recombinant Antibody; scFv Fragment (HPAB-N0367-YC-S(P)) (HPAB-N0367-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Inhib, FuncS
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- Mouse Anti-MIC Recombinant Antibody; Fab Fragment (HPAB-N0369-YC-F(E)) (HPAB-N0369-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Inhib
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- Human Anti-MIC Recombinant Antibody; Fab Fragment (HPAB-N0368-YC-F(E)) (HPAB-N0368-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Inhib, FuncS
Compare
- Mouse Anti-MIC Recombinant Antibody; Fab Fragment (HPAB-N0367-YC-F(E)) (HPAB-N0367-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Inhib, FuncS
Compare
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For Research Use Only. Not For Clinical Use.
Background
MIC (e.g., MICA, MICB) is a ligand for NKG2D, a receptor that is expressed on most human NK cells, γδ T cells, and CD8+ T cells. While NKG2D ligands are not usually found on healthy tissues, various forms of cellular stress, including DNA damage, upregulate ligand expression, resulting in their frequent detection in multiple solid and hematologic malignancies,including melanoma.