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MPL

Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation.
Protein class

Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Erythroid cells, Excitatory neurons, Oligodendrocytes)

Immune cell specificity

Immune cell enhanced (neutrophil)

Cell line specificity

Cell line enriched (HEL)

Interaction

Homodimer (PubMed:25538044). Interacts with ATXN2L.

Molecular function

Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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