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MUC2
Anti-MUC2 Recombinant Antibody Products
- Mouse Anti-MUC2 Recombinant Antibody (MOB-0112F) (MOB-0112F)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Mouse Anti-MUC2 Recombinant Antibody (MOB-0113F) (MOB-0113F)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Derivation: Rabbit
- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, FC
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- Mouse Anti-MUC2 Recombinant Antibody (VS3-WK857) (VS3-WK857)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC
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- Mouse Anti-MUC2 Recombinant Antibody (VS3-WK858) (VS3-WK858)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC
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- A*02:01/Human Mucin2 (LLNQLQVNL) MHC Pentamer (MHC-YF571)
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- Class: Class I
- Antigen: Mucin2
- Antigen Species: Human
- Peptide: LLNQLQVNL
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- A*02:01/Human Mucin2 (MLWGWREHV) MHC Pentamer (MHC-YF572)
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- Class: Class I
- Antigen: Mucin2
- Antigen Species: Human
- Peptide: MLWGWREHV
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, FC, IF, IHC, IP
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, ICC, IP, FC
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- Anti-MUC2 Immunohistochemistry Kit (VS-0325-XY1395)
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- Species Reactivity: Human, Mouse, Rat
- Target: MUC2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis.
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Intestinal goblet cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Homotrimer; disulfide-linked. Dimerizes in the endoplasmic reticulum via its C-terminal region and polymerizes via its N-terminal region by disulfide-linked trimerization. Interacts with FCGBP. Interacts with AGR2; disulfide-linked. (Microbial infection) Interacts in vitro with L.monocytogenes internalin proteins InlB, InlC and InlJ; for InlC binding is slightly better at pH 5.5, (the pH of the intestine) than at pH 7.4.
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