Secreted
Cell type enriched (Plasma cells)
Group enriched (plasmacytoid DC, memory B-cell)
Group enriched (Karpas-707, RPMI-8226)
Part of the ER chaperone complex, a multi-protein complex in the endoplasmic reticulum containing a large number of molecular chaperones which associates with unassembled incompletely folded immunoglobulin heavy chains (By similarity). Isoform 2 interacts with CASP2 and CASP9. Interacts with HSP90B1 and PDIA3 in a calcium-dependent manner (By similarity).
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For Research Use Only. Not For Clinical Use.