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MAP3K15

The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses. [provided by RefSeq, Jul 2010]
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Theca cells, Granulosa cells, Collecting duct cells, Cone photoreceptor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (A549, HAP1, HEK93, JURKAT, REH, SuSa)

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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