Anti-NTRK1 Recombinant Antibody Products

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Anti-NTRK1 Products

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For Research Use Only. Not For Clinical Use.

At Creative Biolabs, we are at the forefront of providing global researchers and pharmaceutical companies with cutting-edge anti-NTRK1 recombinant antibody products. Our commitment to scientific excellence ensures high-quality, reliable reagents essential for groundbreaking discoveries in oncology and neurobiology, accelerating your research and development efforts.

NTRK1: A Key Therapeutic Target for Cancer Treatment

Neurotrophic Tyrosine Receptor Kinase 1 (NTRK1) is a critical receptor tyrosine kinase involved in neuronal development and survival. Aberrant NTRK1 gene fusions act as powerful oncogenic drivers across various tumor types, including lung, colorectal, and thyroid cancers. Extensive research has firmly established NTRK1 as a well-validated therapeutic target, with ongoing studies exploring its role in enhancing immune checkpoint blockade efficacy, underscoring its significant potential for novel cancer treatments.

Alternative Names

Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; tropomyosin receptor kinase A; high affinity nerve growth factor receptor; TRK; TRK1; TRKA; Trk-A; p140-TrkA.

Background

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Anti-NTRK1 rAb Products

Creative Biolabs offers highly validated anti-NTRK1 recombinant antibodies, expertly developed to provide unmatched specificity and robust performance. Leveraging advanced recombinant expression systems, our antibodies exhibit superior purity and lot-to-lot reproducibility, alongside exceptional binding characteristics that ensure minimal off-target effects. These premium reagents are ideal for a broad spectrum of research applications, including Western blotting, IHC, and various functional assays, guaranteeing dependable outcomes.

Table 1. Featured anti-NTRK1 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Our anti-NTRK1 recombinant antibody products undergo stringent quality control measures to guarantee optimal performance. Each batch is validated through a comprehensive panel of tests, including ELISA, flow cytometry, and binding kinetics, to confirm specificity, sensitivity, and functional activity. This meticulous process ensures that our antibodies meet the highest industry standards, providing you with confidence in your experimental outcomes.

Customer Reviews

Excellent

Ma***t
Recombinant Mouse Anti-TrkA Antibody (MNAC13) (PABX-182)

The anti-NTRK1 recombinant antibody from Creative Biolabs significantly accelerated our in vitro studies. Its consistent performance and high specificity across multiple experiments were truly impressive. A reliable product that has become indispensable in our lab's workflow. Highly recommended for any NTRK1-related research.

22/Oct/2024

Excellent

Di***o
Human Anti-NTRK1 Recombinant Antibody (clone CRB0036) (HPAB-AP400-YC)

We've incorporated Creative Biolabs' anti-NTRK1 antibody into our diagnostic assay development, and the results have been outstanding. The sensitivity and robust signal we achieved were crucial for detecting low-level NTRK1 expression in challenging samples. The product's stability also ensured consistent performance over time, which is critical for our application.

22/Jan/2025

Excellent

Me***y
Human Anti-NTRK1 Recombinant Antibody (clone CRB0069) (HPAB-AP401-YC)

For our preclinical drug screening, the anti-NTRK1 recombinant antibody provided by Creative Biolabs offered exceptional utility. Its reliable binding affinity allowed us to accurately quantify NTRK1 levels and assess the efficacy of our candidate inhibitors. The ease of use and compatibility with various platforms made our research much more efficient.

17/May/2025

rAb Production

Our anti-NTRK1 recombinant antibodies are manufactured in state-of-the-art facilities utilizing advanced cell line development and bioreactor technologies. This ensures large-scale, cost-effective production while maintaining superior product integrity and purity. Our robust manufacturing process adheres to strict quality guidelines, enabling us to consistently provide a reliable supply of high-quality antibodies.

Featured Anti-NTRK1 Recombinant Antibody Production Platforms
Fig.2 Milligram-scale anti-NTRK1 recombinant antibody production.

Fig.3 Gram-scale anti-NTRK1 recombinant antibody production.

rAb Modalities

Creative Biolabs offers anti-NTRK1 recombinant antibodies in various formats, including unconjugated, biotinylated, and fluorescently labeled options, providing versatile tools for a wide range of research applications.

Fig.4 Full-length anti-NTRK1 recombinant antibody production and modalities.

NTRK1-Targeted Drug Information

Table 2. Public drug targeting NTRK1.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs is dedicated to empowering your research with premium anti-NTRK1 recombinant antibody products. Our expertise and comprehensive portfolio are designed to meet the evolving demands of oncology research and therapeutic development. To learn more about how our innovative solutions can support your projects or to discuss specific requirements, please do not hesitate to contact us. Our scientific team is ready to assist you.

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