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NUDT5
Loading...Anti-NUDT5 Products
- AbPlus™ Anti-NUDT5 Magnetic Beads (VS-0724-YC637) (VS-0724-YC637)
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- Target: NUDT5
- Target Species: Human
- Application: IP, Protein Purification
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- Recombinant Mouse Anti-Human NUDT5 Antibody (MOB-2209MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, FC
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- Anti-NUDT5 Immunohistochemistry Kit (VS-0525-XY5040)
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- Species Reactivity: Human
- Target: NUDT5
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer (PubMed:27257257, PubMed:17052728, PubMed:18462755, PubMed:21768126). Interacts with PARG (PubMed:27257257).
Molecular function
Hydrolase, RNA-binding, Transferase
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