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NFKBIL1

This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class

Disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (ASC TERT1, HBEC3-KT, HEK93, JURKAT, U-266/70, U-266/84, U-698)

Interaction

Interacts with CACTIN (via N-terminal domain); the interaction occurs in a proinflammatory-independent manner.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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