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OAT

Anti-OAT Products
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- Species Reactivity: Human
- Application: ELISA, ICC/IF, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, IP, IHC
- Anti-OAT Immunohistochemistry Kit (VS-0525-XY5066)
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- Species Reactivity: Human
- Target: OAT
- Application: IHC
- Anti-Mouse OAT Immunohistochemistry Kit (VS-0525-XY5067)
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- Species Reactivity: Human, Mouse, Rat
- Target: OAT
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homohexamer.
Molecular function
Aminotransferase, Transferase
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