PDCD1
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
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- Species Reactivity: Mouse
- Type: IgG2b
- Application: BL
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IHC
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- Species Reactivity: Mouse
- Type: IgG2a
- Application: BL, WB
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- Species Reactivity: Mouse
- Type: IgG
- Application: BL, WB
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- Species Reactivity: Mouse
- Type: IgG2a
- Application: BL, FC
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- Species Reactivity: Human
- Application: FC
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- Species Reactivity: Human
- Type: IgG2
- Application: Neut, WB
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- Species Reactivity: Mouse
- Type: IgG2
- Application: BL, FC
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- Species Reactivity: Human
- Type: IgG1
- Application: BL, WB
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- Species Reactivity: Human
- Type: IgG1, κ
- Application: Neut
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- Species Reactivity: Human
- Type: IgG2
- Application: Neut, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FC, ICC, IF, IHC
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Human IgG4 kappa
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human, Rhesus monkey
- Type: IgG2b
- Application: BL
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG4 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
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- Derivation: scFv phagemid library
- Type: Human antibody
- Application: ELISA, FuncS
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, WB
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG4, κ
- Application: Inhib, Agonist
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus
- Type: Humanized IgG4
- Application: ELISA, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG4
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, FuncS
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, FuncS
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- Derivation: Caninized
- Species Reactivity: Canine
- Type: IgG2, κ
- Application: ELISA, IHC, FC, IP, IF, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG4, κ
- Application: ELISA, IHC, FC, IP, IF, BL
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human
- Type: Chimeric (Mouse/Human) Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, SPR
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Cynomolgus and rhesus
- Type: Humanized antibody
- Application: FC
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Cynomolgus and rhesus
- Type: Humanized antibody
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Cynomolgus and rhesus
- Type: Humanized antibody
- Application: FC
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- Species Reactivity: Cynomolgus and rhesus
- Application: FC
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- Species Reactivity: Cynomolgus and rhesus
- Application: FC
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- Derivation: scFv phagemid library
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Cynomolgus and rhesus
- Application: FC
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- Derivation: scFv phagemid library
- Type: Human antibody
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, WB
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human
- Type: Chimeric (Mouse/Human) antibody
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Derivation: scFv phagemid library
- Type: Human antibody
- Application: ELISA
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- Derivation: scFv phagemid library
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, ELISA
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- Derivation: scFv phagemid library
- Type: Human antibody
- Application: ELISA
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More Infomation
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