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PLA2G10

Anti-PLA2G10 Products
- Anti-Human sPLA2-X Recombinant Antibody (8D9) (TAB-490CT)
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: ELISA, Inhibit
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: IF, FC, Biosensors, FuncS
- Recombinant Anti-human PLA2G10 Antibody (MOB-777)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FuncS
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Species Reactivity: Human
- Type: Antibody
- Recombinant Anti-human PLA2G10 Antibody Fab Fragment (MOB-777-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, FuncS
- Recombinant Anti-human PLA2G10 Antibody scFv Fragment (MOB-777-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: Neut, WB, FuncS
- Recombinant Human Anti-human PLA2G10 Antibody Fab Fragment (MHH-777-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: IP, IF, FuncS
- Recombinant Human Anti-human PLA2G10 Antibody scFv Fragment (MHH-777-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: FC, ELISA, FuncS
- Anti-Human sPLA2-X Recombinant Antibody Fab Fragment (8D9) (TAB-490CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: ELISA, Inhibit
- Anti-Human sPLA2-X Recombinant Antibody Fab Fragment (9C12) (TAB-491CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: ELISA, Inhibit
- Anti-Human sPLA2-X Recombinant Antibody (9C12) (TAB-491CT)
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: ELISA, Inhibit
- Anti-Human sPLA2-X Recombinant Antibody scFv Fragment (8D9) (TAB-490CT-S(P))
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: ELISA, Inhibit
- Anti-Human sPLA2-X Recombinant Antibody scFv Fragment (9C12) (TAB-491CT-S(P))
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: ELISA, Inhibit
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: Antigen-Sweeping In Vivo.
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids 1, 2. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls.
Protein class
Enzymes, FDA approved drug targets, Metabolic proteins, RAS pathway related proteins
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Distal enterocytes, Paneth cells, Intestinal goblet cells, Exocrine glandular cells, Gastric mucus-secreting cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BEWO, CAPAN-2, HaCaT, MCF7, OE19, SK-BR-3)
Interaction
Interacts with PLA2R1; this interaction mediates PLA2G10 clearance and inactivation.
Molecular function
Hydrolase
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