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PLA2G7

In the blood Lp-PLA2 travels mainly with low-density lipoprotein (LDL). Less than 20% is associated with high-density lipoprotein HDL. Several lines of evidence suggest that HDL-associated Lp-PLA2 may substantially contribute to the HDL antiatherogenic activities.
Protein class

Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets

Predicted location

Secreted

Single cell type specificity

Group enriched (Hofbauer cells, Macrophages)

Immune cell specificity

Immune cell enhanced (classical monocyte)

Cell line specificity

Cell line enhanced (NTERA-2, PC-3, RT4, U-2 OS)

Molecular function

Hydrolase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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