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PPP3R2

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For Research Use Only. Not For Clinical Use.


Background

Protein class

FDA approved drug targets, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Group enriched (Spermatocytes, Early spermatids, Late spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Forms a complex composed of a calmodulin-dependent catalytic subunit (also known as calcineurin A) and a regulatory Ca(2+)-binding subunit (also known as calcineurin B). There are three catalytic subunits, each encoded by a separate gene (PPP3CA, PPP3CB, and PPP3CC) and two regulatory subunits which are also encoded by separate genes (PPP3R1 and PPP3R2) (By similarity). Interacts with SPATA33 (via PQIIIT motif) (PubMed:34446558).

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