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PSD

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Anti-PSD Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Cone photoreceptor cells, Rod photoreceptor cells, Bipolar cells, Endometrial stromal cells, Excitatory neurons, Inhibitory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HSkMC, MOLT-4, SCLC-21H, SH-SY5Y)

Interaction

Interacts with ACTN1. Interacts (ARF6-bound form) with KCNK1; does not interact with KCNK1 in the absence of ARF6 (By similarity).

Molecular function

Guanine-nucleotide releasing factor

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