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PTGS1
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression.
Protein class
Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (granulocytes, Glandular and luminal cells, Endometrial ciliated cells, Hepatic stellate cells, Suprabasal keratinocytes, Macrophages)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Cell line enhanced (ASC diff, ASC TERT1, BJ, BJ hTERT+, HEL, HMC-1)
Interaction
Homodimer.
Molecular function
Dioxygenase, Oxidoreductase, Peroxidase
More Types Infomation
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC, IP
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA
-
- Species Reactivity: Mouse, Rat, Human, Ovine
- Type: Mouse IgG2b, κ
- Application: WB, IP, IF, IHC-P, FC
- Recombinant Anti-Human PTGS1 Antibody scFv Fragment (MOB-1999z-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FC, FuncS
- Recombinant Anti-Human PTGS1 Antibody Fab Fragment (MOB-1999z-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, RIA, FuncS
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, IHC-P, ICC/IF, FC
- Rabbit Anti-PTGS1 Polyclonal Antibody (MRO-1787-CN) (MRO-1787-CN)
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF, IP
- Mouse Anti-PTGS1 Recombinant Antibody (VS-0224-XY103) (VS-0224-XY103)
-
- Species Reactivity: Human, Mouse, Sheep, Rat
- Type: Mouse IgG2b
- Application: ELISA, WB, IF, IHC, ICC
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IHC, FC, IP
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: ELISA, WB, FC
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For Research Use Only. Not For Clinical Use.