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RAET1E

Retinoic acid early transcript 1E (RAET1E) is a cell surface glycoprotein encoded by RAET1E gene located on the chromosome 6. Which binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
RAET1E
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Squamous epithelial cells, Respiratory ciliated cells, Basal respiratory cells, Early spermatids, Suprabasal keratinocytes, Late spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HBEC3-KT, HeLa, hTCEpi, SiHa, U-87 MG)

Interaction

Binds to KLRK1/NKG2D. (Microbial infection) Contrary to other family members, does not interact with CMV glycoprotein UL16.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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