Intracellular, Membrane (different isoforms)
Cell type enhanced (Squamous epithelial cells, Respiratory ciliated cells, Basal respiratory cells, Early spermatids, Suprabasal keratinocytes, Late spermatids)
Not detected in immune cells
Cell line enhanced (HBEC3-KT, HeLa, hTCEpi, SiHa, U-87 MG)
Binds to KLRK1/NKG2D. (Microbial infection) Contrary to other family members, does not interact with CMV glycoprotein UL16.
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For Research Use Only. Not For Clinical Use.