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RAPGEF5
Anti-RAPGEF5 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
Protein class
Plasma proteins, RAS pathway related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Excitatory neurons, Inhibitory neurons, Microglial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (Daudi, HUVEC TERT2, SCLC-21H, TIME, U-698)
Molecular function
Guanine-nucleotide releasing factor
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