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SEMA4D
Enables identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase signaling; regulation of neuron projection development; and regulation of phosphate metabolic process. Is integral component of plasma membrane.
Protein class
CD markers, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocytes, NK-cells, T-cells, dendritic cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HDLM-2, HMC-1, JURKAT, MOLT-4)
Interaction
Homodimer (PubMed:20877282). Interacts with PLXNB2 (By similarity). Interacts with PLXNB1 (PubMed:10520995).
Molecular function
Developmental protein, Receptor
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, ICC
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- Species Reactivity: Human
- Application: ELISA, FC, IP
-
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, ELISA, FC, BL
-
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, ELISA, FC, BL
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP442-YC-S(P)) (HPAB-AP442-YC-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, Block, Neut, FuncS
- Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP443-YC-F(E)) (HPAB-AP443-YC-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, Block
- Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP442-YC-F(E)) (HPAB-AP442-YC-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, Block, Neut, FuncS
- Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP440-YC-F(E)) (HPAB-AP440-YC-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, Block, Neut, FuncS
- Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-0049-WJ-S(P)) (HPAB-0049-WJ-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: FC, ELISA
- Human Anti-SEMA4D Recombinant Antibody (HPAB-AP443-YC) (HPAB-AP443-YC)
-
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, Block
- Mouse Anti-SEMA4D Recombinant Antibody (HPAB-AP442-YC) (HPAB-AP442-YC)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG2b
- Application: ELISA, Block, Neut, FuncS
- Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-0049-WJ-F(E)) (HPAB-0049-WJ-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: FC, ELISA
- Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP440-YC-S(P)) (HPAB-AP440-YC-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, Block, Neut, FuncS
- Mouse Anti-SEMA4D Recombinant Antibody (HPAB-0049-WJ) (HPAB-0049-WJ)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: FC, ELISA, IHC, FuncS, Inhib
-
- Species Reactivity: Human
- Type: Humanized IgG
- Application: WB
-
- Species Reactivity: Human
- Type: Humanized IgG
- Application: WB
- Mouse Anti-SEMA4D Recombinant Antibody (HPAB-AP440-YC) (HPAB-AP440-YC)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG2b
- Application: ELISA, Block, Neut, FuncS
-
- Species Reactivity: Human
- Type: Humanized scFv
- Application: WB, ELISA, FC, BL
-
- Species Reactivity: Human
- Type: Humanized scFv
- Application: WB, ELISA, FC, BL
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For Research Use Only. Not For Clinical Use.