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SEMA4D

Anti-SEMA4D Products
- Mouse Anti-SEMA4D Recombinant Antibody (HPAB-0934WJ) (HPAB-0934WJ)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: Neut
- Human Anti-SEMA4D Recombinant Antibody (HPAB-0935WJ) (HPAB-0935WJ)
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized IgG1
- Application: Neut, ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: WB
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: WB
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: WB, ELISA, FC, BL
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: WB, ELISA, FC, BL
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- Species Reactivity: Human
- Type: Humanized IgG4
- Application: ELISA, FC
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- Species Reactivity: Human, Mouse
- Type: Human IgG4 (S228P)
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, WB, FC
- Human Anti-SEMA4D Recombinant Antibody (HPAB-AP446-YC) (HPAB-AP446-YC)
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- Species Reactivity: Human
- Type: Human IgG4
- Application: ELISA, Block
- Human Anti-SEMA4D Recombinant Antibody (HPAB-AP447-YC) (HPAB-AP447-YC)
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- Species Reactivity: Human
- Type: Human IgG4
- Application: ELISA, Block
- Human Anti-SEMA4D Recombinant Antibody (HPAB-AP448-YC) (HPAB-AP448-YC)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
- Mouse Anti-SEMA4D Recombinant Antibody (HPAB-AP440-YC) (HPAB-AP440-YC)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2b
- Application: ELISA, Block, Neut, FuncS
- Mouse Anti-SEMA4D Recombinant Antibody (HPAB-AP442-YC) (HPAB-AP442-YC)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2b
- Application: ELISA, Block, Neut, FuncS
- Human Anti-SEMA4D Recombinant Antibody (HPAB-AP443-YC) (HPAB-AP443-YC)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, Block
- Human Anti-SEMA4D Recombinant Antibody (HPAB-AP444-YC) (HPAB-AP444-YC)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, Block
- Human Anti-SEMA4D Recombinant Antibody (HPAB-AP445-YC) (HPAB-AP445-YC)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Block
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, ELISA, FC, BL
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, ELISA, FC, BL
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- Species Reactivity: Human
- Application: ELISA, FC, IP
- Mouse Anti-SEMA4D Recombinant Antibody (HPAB-0049-WJ) (HPAB-0049-WJ)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: FC, ELISA, IHC, FuncS, Inhib
- Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-0049-WJ-S(P)) (HPAB-0049-WJ-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: FC, ELISA
- Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-0935WJ-F(E)) (HPAB-0935WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: Neut, ELISA
- Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP448-YC-F(E)) (HPAB-AP448-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP440-YC-S(P)) (HPAB-AP440-YC-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, Block, Neut, FuncS
- Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP442-YC-S(P)) (HPAB-AP442-YC-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, Block, Neut, FuncS
- Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP443-YC-S(P)) (HPAB-AP443-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC, Block
- Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-0049-WJ-F(E)) (HPAB-0049-WJ-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: FC, ELISA
- Mouse Anti-NHP SEMA4D Recombinant Antibody (clone A8) (VS-1024-XY70)
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- Species Reactivity: Human, Mouse, Non-human primate
- Type: Mouse IgG1, kappa
- Application: IF, FC
- Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-0934WJ-S(P)) (HPAB-0934WJ-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: Neut
- Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-0935WJ-S(P)) (HPAB-0935WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized scFv
- Application: Neut, ELISA
- Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-0934WJ-F(E)) (HPAB-0934WJ-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: Neut
- Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP442-YC-F(E)) (HPAB-AP442-YC-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, Block, Neut, FuncS
- Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP443-YC-F(E)) (HPAB-AP443-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, Block
- Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP444-YC-F(E)) (HPAB-AP444-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, Block
- Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP445-YC-F(E)) (HPAB-AP445-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Block
- Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP446-YC-F(E)) (HPAB-AP446-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Block
- Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP447-YC-F(E)) (HPAB-AP447-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Block
- Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP444-YC-S(P)) (HPAB-AP444-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC, Block
- Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP445-YC-S(P)) (HPAB-AP445-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Block
- Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP446-YC-S(P)) (HPAB-AP446-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Block
- Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP447-YC-S(P)) (HPAB-AP447-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Block
- Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP448-YC-S(P)) (HPAB-AP448-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP440-YC-F(E)) (HPAB-AP440-YC-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, Block, Neut, FuncS
- CytoStream™ Rat Anti-SEMA4D Recombinant Antibody (clone BMA-12) (VS-0225-XY197)
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- Species Reactivity: Mouse
- Type: Rat IgG2a, lambda
- Application: FC
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- Species Reactivity: Human, Mouse
- Target: SEMA4D
- Host Animal: Mouse
- Application: ELISA, FC, Neut, Cell-uptake
- Anti-SEMA4D Immunohistochemistry Kit (VS-0525-XY6444)
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- Species Reactivity: Human
- Target: SEMA4D
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, ICC
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For Research Use Only. Not For Clinical Use.
Background
SEMA4D (Semaphorin 4D) is a Protein Coding gene. Diseases associated with SEMA4D include Hemorrhagic Fever With Renal Syndrome and Osteonecrosis Of The Jaw. Among its related pathways are Development Slit-Robo signaling and Semaphorin interactions. Gene Ontology (GO) annotations related to this gene include receptor binding and transmembrane signaling receptor activity. An important paralog of this gene is SEMA4C.

Protein class
CD markers, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocytes, NK-cells, T-cells, dendritic cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HDLM-2, HMC-1, JURKAT, MOLT-4)
Interaction
Homodimer (PubMed:20877282). Interacts with PLXNB2 (By similarity). Interacts with PLXNB1 (PubMed:10520995).
Molecular function
Developmental protein, Receptor
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