Loading...
SLAMF7
The surface antigen CD319 (SLAMF7) is a robust marker of normal plasma cells and malignant plasma cells in multiple myeloma. In contrast to CD138 (the traditional plasma cell marker), CD319/SLAMF7 is much more stable and allows robust isolation of malignant plasma cells from delayed or even cryopreserved samples.
Protein class
CD markers, FDA approved drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Plasma cells, monocytes, NK-cells, dendritic cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enriched (U-266/70)
Interaction
Isoform 1 binds to SH2D1A when its cytoplasmic tail is phosphorylated in the presence of FYN (in vitro); low affinity binding, the physiological relevance of the interaction is questioned. Interacts with SH2D1B; in NK cells (PubMed:16339536). Interacts (via ITSM phosphorylated on Tyr-302) with SH2D1B, PTPN6/SHP-1, PTPN11/SHP-2, INPP5D/SHIP1, CSK and FYN (By similarity).
Molecular function
Receptor
More Types Infomation
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
-
- Species Reactivity: Mouse
- Type: IgG
- Application: ELISA
-
- Species Reactivity: Human
- Type: IgG
- Application: ELISA
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC
- Mouse Anti-SLAMF7 Recombinant Antibody (HPAB-AP798-YC) (HPAB-AP798-YC)
-
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, FC, IHC, Inhib
- Human Anti-SLAMF7 Recombinant Antibody; Fab Fragment (HPAB-AP800-YC-F(E)) (HPAB-AP800-YC-F(E))
-
- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human
- Type: Chimeric (Mouse/Human) Fab
- Application: ELISA, FC, IHC, Inhib, ADCC, FuncS
- Human Anti-SLAMF7 Recombinant Antibody; Fab Fragment (HPAB-AP799-YC-F(E)) (HPAB-AP799-YC-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, IHC, Inhib, ADCC, FuncS
- Mouse Anti-SLAMF7 Recombinant Antibody; Fab Fragment (HPAB-AP798-YC-F(E)) (HPAB-AP798-YC-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, IHC, Inhib
- Mouse Anti-SLAMF7 Recombinant Antibody; Fab Fragment (HPAB-AP797-YC-F(E)) (HPAB-AP797-YC-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, IHC, Inhib
- Mouse Anti-SLAMF7 Recombinant Antibody; Fab Fragment (HPAB-AP796-YC-F(E)) (HPAB-AP796-YC-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, IHC, Inhib
-
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: FuncS, IF, Neut, ELISA, FC, IP
- Human Anti-SLAMF7 Recombinant Antibody (clone to-Ilo jumap); scFv Fragment (HPAB-642-FY-S(P))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Activ
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: IF, IHC, Inhib
- Mouse Anti-SLAMF7 Recombinant Antibody; scFv Fragment (HPAB-AP797-YC-S(P)) (HPAB-AP797-YC-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, IHC, Inhib
- Mouse Anti-SLAMF7 Recombinant Antibody; scFv Fragment (HPAB-AP796-YC-S(P)) (HPAB-AP796-YC-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, IHC, Inhib
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG2a
- Application: Activ
- Mouse Anti-SLAMF7 Recombinant Antibody (HPAB-AP797-YC) (HPAB-AP797-YC)
-
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, FC, IHC, Inhib
- Mouse Anti-SLAMF7 Recombinant Antibody (HPAB-AP796-YC) (HPAB-AP796-YC)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FC, IHC, Inhib
- Human Anti-SLAMF7 Recombinant Antibody (clone Elo-g2a); Fab Fragment (HPAB-642-FY-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Activ
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.