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SLC45A2
This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated with variations in skin and hair color. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class
Disease related genes, Human disease related genes, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Melanocytes, Inhibitory neurons, Late spermatids, Oligodendrocytes, Excitatory neurons, Early spermatids, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (SK-MEL-30)
More Types Infomation
- PE-A*02:01/Human SLC45A2 (SLYSYFQKV) MHC Tetramer (MHC-CN1426)
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- Class: Class I
- Antigen: SLC45A2
- Antigen Species: Human
- Peptide: SLYSYFQKV
- Conjugate: PE
- A*02:01/Human SLC45A2 (SLYSYFQKV) MHC Monomer (MHC-YF291)
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- Class: Class I
- Antigen: SLC45A2
- Antigen Species: Human
- Peptide: SLYSYFQKV
- Conjugate: Biotin
- Recombinant Mouse Anti-Human SLC45A2 Antibody (MOB-1577MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.