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SND1
This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC).
Protein class
Cancer-related genes, Enzymes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Cytotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Forms a ternary complex with STAT6 and POLR2A (PubMed:12234934). Associates with the RNA-induced silencing complex (RISC) (PubMed:14508492, 28546213). Interacts with the RISC components AGO2, FMR1 and TNRC6A (PubMed:14508492, 28546213). Interacts with GTF2E1 and GTF2E2 (PubMed:7651391). Interacts with PIM1 (PubMed:9809063). Interacts with STAT5 (By similarity). Interacts with SYT11 (via C2 2 domain); the interaction with SYT11 is direct (By similarity). (Microbial infection) Interacts with EAV NSP1 (PubMed:12917451). Binds to acidic transactivation domain of EBNA2 (PubMed:7651391).
Molecular function
Endonuclease, Hydrolase, Nuclease
More Types Infomation
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IP, FuncS
- Recombinant Anti-human SND1 Antibody scFv Fragment (MOB-914-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: IF, Neut, FuncS
- Recombinant Human Anti-human SND1 Antibody Fab Fragment (MHH-914-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IF, FuncS
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, ICC/IF, WB
- Recombinant Human Anti-human SND1 Antibody scFv Fragment (MHH-914-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IP, FuncS
- Recombinant Anti-human SND1 Antibody Fab Fragment (MOB-914-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: RIA, WB, FuncS
- Recombinant Anti-human SND1 Antibody (MOB-914)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IF, FuncS
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Mouse Anti-SND1 Recombinant Antibody (clone 2D7) (VS3-XY1450)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.