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SNRPA
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Interacts with SFPQ; component of a snRNP-free complex with SFPQ.
Molecular function
Ribonucleoprotein, RNA-binding
More Types Infomation
- PE-A*02:01/Human SNRPA (NQFPGFKEV) MHC Tetramer (MHC-LC1938)
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- Class: Class I
- Antigen: SNRPA
- Antigen Species: Human
- Peptide: NQFPGFKEV
- Conjugate: PE
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
- Chicken Anti-SNRPA Antibody (clone U13D12), mRNA (FAMAB-0008JF-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Application: ICC/IF, IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IP, ICC/IF
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, ELISA, IF, IHC, IP
- Chicken Anti-SNRPA Recombinant Antibody (clone U13D12); scFv Fragment (FAMAB-0008JF-S(P))
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- Derivation: Chicken phage display scFv library
- Species Reactivity: Human
- Type: Chicken scFv
- Application: IB, WB, ELISA, FuncS
- Chicken Anti-SNRPA Recombinant Antibody (clone U13D12); Fab Fragment (FAMAB-0008JF-F(E))
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- Derivation: Chicken phage display scFv library
- Species Reactivity: Human
- Type: Chicken Fab
- Application: IB, WB, ELISA, FuncS
- Chicken Anti-SNRPA Recombinant Antibody (clone U13D12) (FAMAB-0008JF)
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- Derivation: Chicken phage display scFv library
- Species Reactivity: Human
- Application: WB, IF, Inhib, FuncS, IHC
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For Research Use Only. Not For Clinical Use.