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SUV39H2
Anti-SUV39H2 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
Enables S-adenosyl-L-methionine binding activity; histone methyltransferase activity (H3-K9 specific); and zinc ion binding activity. Involved in chromatin assembly or disassembly and chromatin remodeling. Acts upstream of or within cellular response to hypoxia and negative regulation of transcription by RNA polymerase II. Located in chromatin.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with SMAD5. The large PER complex involved in the histone methylation is composed of at least PER2, CBX3, TRIM28, SUV39H1 and/or SUV39H2; CBX3 mediates the formation of the complex.
Molecular function
Chromatin regulator, Methyltransferase, Repressor, Transferase
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