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SHC2

Protein class

RAS pathway related proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Hepatocytes, Oligodendrocyte precursor cells, Horizontal cells, Hepatic stellate cells, Adipocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (EFO-21, HHSteC, SCLC-21H, SH-SY5Y)

Interaction

Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated, binds to GRB2.

More Types Infomation

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