Loading...
TH
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Protein class
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Endometrial stromal cells, Leydig cells, Syncytiotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (PC-3, SK-BR-3)
Interaction
Homotetramer (Ref. 18, PubMed:24947669). Interacts (when phosphorylated at Ser-19) with YWHAG; one YWHAG dimer bounds to one TH tetramer, this interaction may influence the phosphorylation and dephosphorylation of other sites (PubMed:24947669).
Molecular function
Monooxygenase, Oxidoreductase
More Types Infomation
Related Diseases
Amphetamine Addiction
Alcoholism
- H-2Kk/Human TH (FETFEAKI) MHC Tetramer (MHC-CN1272)
-
- Class: Class I
- Antigen: TH
- Antigen Species: Human
- Peptide: FETFEAKI
- Conjugate: Unconjugated
- FITC-H-2Kk/Human TH (FETFEAKI) MHC Tetramer (MHC-CN1271)
-
- Class: Class I
- Antigen: TH
- Antigen Species: Human
- Peptide: FETFEAKI
- Conjugate: FITC
- APC-H-2Kk/Human TH (FETFEAKI) MHC Tetramer (MHC-CN1270)
-
- Class: Class I
- Antigen: TH
- Antigen Species: Human
- Peptide: FETFEAKI
- Conjugate: APC
- PE-H-2Kk/Human TH (FETFEAKI) MHC Tetramer (MHC-CN1269)
-
- Class: Class I
- Antigen: TH
- Antigen Species: Human
- Peptide: FETFEAKI
- Conjugate: PE
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC
- Rabbit Anti-TH Recombinant Antibody (clone CBACN-568) (MRO-1546-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
- Rabbit Anti-TH Recombinant Antibody (clone CBACN-567) (MRO-1545-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, ICC, FC
- Mouse Anti-TH Recombinant Antibody (clone 26H11) (MOB-2042z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ICC, IF
- Rabbit Anti-TH Recombinant Antibody (clone AFY0070) (MOR-0099-FY)
-
- Species Reactivity: Mouse, Rat
- Type: Rabbit IgG
- Application: ICC, IF, IHC-P, WB
- Rabbit Anti-TH Polyclonal Antibody (MRO-2249-CN) (MRO-2249-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
- Rabbit Anti-TH Recombinant Antibody (clone R01-3E4) (VS3-FY1925)
-
- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, IF
- Mouse Anti-TH Recombinant Antibody (clone 4B1) (VS3-WK1590)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: IHC-P, WB
- Chicken Anti-TH Polyclonal IgY (BRD-0734MZ)
-
- Species Reactivity: Human, Rat, Mouse
- Type: Chicken antibody
- Application: ICC/IF, IHC, WB
- Rabbit Anti-TH Recombinant Antibody (VS3-CJ456) (VS3-CJ456)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IHC, FC
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.