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THPO
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- Mouse Anti-THPO Antibody (clone TN1), mRNA (PABZ-075-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-THPO Recombinant Antibody (clone 1B11) (VS3-XY1514)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, WB, FC
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- Mouse Anti-THPO Recombinant Antibody (clone C10-B11) (VS3-XY1515)
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- Species Reactivity: Human
- Type: Mouse IgG2a
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- Anti-Dog (Canine) Thrombopoietin Antibody (MOB-0207MC)
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- Species Reactivity: Dog (Canine), Human
- Application: WB
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- Mouse Anti-THPO Recombinant Antibody (clone YC167) (MOB-0208MC)
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- Species Reactivity: Canine
- Type: Mouse IgG
- Application: WB, ICC, IHC-P, IHC-F, ELISA
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- Recombinant Anti-human THPO Antibody (MOB-973)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, FuncS
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- Recombinant Anti-human THPO Antibody Fab Fragment (MOB-973-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, FC, FuncS
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- Recombinant Anti-human THPO Antibody scFv Fragment (MOB-973-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FC, FuncS
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- Recombinant Mouse Anti-Thrombopoietin Antibody scFv Fragment (TN1) (PABX-178-S (P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, Neut, FuncS
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- Recombinant Mouse Anti-Thrombopoietin Antibody Fab Fragment (TN1 ) (PABX-178-F (E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, Neut, FuncS
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- Recombinant Human Anti-human THPO Antibody Fab Fragment (MHH-973-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, FuncS
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- Recombinant Human Anti-human THPO Antibody scFv Fragment (MHH-973-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IP, FuncS
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For Research Use Only. Not For Clinical Use.
Background
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]
Protein class
Cancer-related genes, Disease related genes
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Hepatocytes, Proximal tubular cells, Late spermatids, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CACO-2, Hep G2, K-562, RPMI-8226)
Molecular function
Cytokine, Hormone
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