Anti-TIM3 Recombinant Antibody Products

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Anti-TIM3 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs proudly presents our cutting-edge anti-TIM3 recombinant antibody products, meticulously engineered to meet the stringent demands of global research and therapeutic development. Our advanced portfolio offers unparalleled specificity and efficacy, empowering scientists worldwide to accelerate their breakthroughs in immunology and disease mechanisms.

TIM3: A Promising Therapeutic Target for Immunotherapy

TIM-3 (T-cell immunoglobulin and mucin domain-containing protein 3), also known as HAVCR2, is a critical immunological checkpoint receptor largely expressed on numerous immune cells, including fatigued T cells, regulatory T cells, and natural killer cells. Extensive research highlights its pivotal role in immune regulation, particularly in mediating T cell exhaustion and promoting immune tolerance in the tumor microenvironment. Understanding TIM3's intricate functions is vital for developing novel immunotherapies against cancer and autoimmune diseases.

Alternative Names

Hepatitis A virus cellular receptor 2; T-cell immunoglobulin and mucin-domain containing-3; HAVCR2; HAVcr-2; KIM-3; TIM-3; TIMD-3; TIMD3; Tim-3; CD366; SPTCL.

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

Anti-TIM3 rAb Products

Our anti-TIM3 recombinant antibody products are meticulously developed to provide researchers with highly specific and potent tools. Leveraging advanced recombinant technology, these antibodies offer superior batch-to-batch consistency, reduced immunogenicity, and enhanced purity compared to traditional polyclonal antibodies. This ensures reliable and reproducible results, accelerating your studies in immune checkpoint blockade, cell-based assays, and therapeutic development.

Table 1. Featured anti-TIM3 recombinant antibody products at Creative Biolabs.

Creative Quality Control

At Creative Biolabs, every anti-TIM3 recombinant antibody follows a rigorous quality control procedure. This includes rigorous validation through techniques such as ELISA, Western Blot, Flow Cytometry, and functional assays to confirm specificity, affinity, and biological activity. Our dedication to excellence guarantees that researchers receive products of the highest quality, guaranteeing dependable performance in critical experiments.

Customer Reviews

Excellent

Ki***a
Anti-Human TIM3 Recombinant Antibody (TSR-022) (TAB-0366CL)

The anti-TIM3 recombinant antibody from Creative Biolabs has significantly advanced our research. Its exceptional specificity and low background noise made our flow cytometry experiments incredibly clear and interpretable. The constant performance across numerous batches has saved us critical time and money, allowing us to concentrate on data analysis rather than debugging.

11/Mar/2024

Excellent

An***n
Anti-Human TIM3 Recombinant Antibody (TSR-022) (TAB-0366CL)

We've been incredibly impressed with the performance of Creative Biolabs' anti-TIM3 antibody in our in vitro functional assays. It consistently delivers robust results, enabling us to precisely modulate TIM-3 signaling. The ease of use and clear protocols provided made integration into our existing workflow seamless, greatly enhancing our experimental efficiency.

10/Jul/2024

Excellent

Sa***i
Mouse Anti-TIM3 Recombinant Antibody (TAB-667CT) (TAB-667CT)

For our therapeutic development program, the anti-TIM3 recombinant antibody from Creative Biolabs has been indispensable. Its high affinity and purity are crucial for our preclinical studies, providing reliable data for lead candidate selection. We appreciate the consistent quality and the comprehensive technical support, which are vital for our long-term research goals.

2/Dec/2024

rAb Production

The manufacturing of our anti-TIM3 recombinant antibodies is executed within advanced mammalian expression systems, thereby ensuring optimal protein folding and critical post-translational modifications essential for biological activity. Our production methodology is characterized by a streamlined and scalable process, adhering rigorously to the highest industry standards, which collectively assures high yield, exceptional purity, and consistent lot-to-lot reproducibility, rendering these products suitable for wide research applications.

Featured Anti-TIM3 Recombinant Antibody Production Platforms
Fig.5 Milligram-scale anti-TIM3 recombinant antibody production.

Fig.6 Gram-scale anti-TIM3 recombinant antibody production.

rAb Modalities

Creative Biolabs offers anti-TIM3 recombinant antibodies in a comprehensive array of modalities, encompassing antibody fragments, bispecific antibodies, and numerous other formats, thereby providing extensive versatility for a wide spectrum of experimental designs and applications.

Fig.7 Full-length anti-TIM3 recombinant antibody production and modalities.

TIM3-Targeted Drug Information

Table 2. Public drug targeting TIM3.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs is dedicated to supporting your scientific endeavors with premium anti-TIM3 recombinant antibody products. We inspire you to browse our broad portfolio and use our experience to make your next breakthrough. Please contact us if you need extensive product information, technical help, or to explore bespoke solutions. Our team of professionals is here to help.