TMEFF2
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IHC, WB, IF
- Human Anti-TMEFF2 Antibody, mRNA (TAB-616CL-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Human IgG4 (S228P)
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC, IHC
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, IHC
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, IHC
- Anti-Human TMEFF2 Recombinant Antibody (AT-19) (TAB-158CQ)
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- Derivation: Human naϊve antibody phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FC, IF
- Anti-Human TMEFF2 Recombinant Antibody scFv Fragment (AT-19) (TAB-158CQ-S(P))
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- Derivation: Human naϊve antibody phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FC, IF
- Anti-Human TMEFF2 Recombinant Antibody Fab Fragment (AT-19) (TAB-158CQ-F(E))
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- Derivation: Human naϊve antibody phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FC, IF
- Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19) (HPAB-0022-LS)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
- Recombinant Anti-Human TMEFF2 Antibody Fab Fragment (MOB-3543z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, FuncS
- Recombinant Anti-Human TMEFF2 Antibody scFv Fragment (MOB-3543z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
- Anti-Human TMEFF2 Recombinant Antibody (TAB-616CL)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Antibody
- Anti-Human TMEFF2 Recombinant Antibody (PQ01 (#001)) (TAB-0284CL)
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- Application: ELISA, WB, FuncS
- Anti-Human TMEFF2 Recombinant Antibody scFv Fragment (PQ01 (#001)) (TAB-0284CL-S(P))
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- Application: ELISA, WB, FuncS
- Anti-Human TMEFF2 Recombinant Antibody Fab Fragment (PQ01 (#001)) (TAB-0284CL-F(E))
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- Application: ELISA, WB, FuncS
- Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19); Fab Fragment (HPAB-0022-LS-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19); scFv Fragment (HPAB-0022-LS-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Antibody Host: Human
- Antibody Reactivity: Human
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P, ICC, IF, FC
- Anti-TMEFF2 Immunohistochemistry Kit (VS-0325-XY2300)
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- Species Reactivity: Human
- Target: TMEFF2
- Application: IHC
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- Species Reactivity: Human
- Target: TMEFF2
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
- Anti-Mouse TMEFF2 Immunohistochemistry Kit (VS-0525-XY7326)
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- Species Reactivity: Human, Mouse
- Target: TMEFF2
- Application: IHC
- Anti-Human TMEFF2 Immunohistochemistry Kit (VS-0525-XY7325)
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- Species Reactivity: Human
- Target: TMEFF2
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Anti-tenb2-vc-MMAE ADC (ADC-117CL)
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- Target: tenb2
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-tenb2-MC-MMAF ADC (ADC-118CL)
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- Target: tenb2
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-TENB2 (clone TMEFF2#19)-MC-MMAF ADC (ADC-119CL)
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- Target: TENB2
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-TENB2 (clone TMEFF2#19)-MC-vc-PAB-MMAE ADC (ADC-120CL)
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- Target: TENB2
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Thio-Anti-TENB2-MC-vc-PAB-MMAE ADC (ADC-158LCT)
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- Target: TENB2
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-TMEFF2 (huPr1)-vcMMAE ADC (ADC-169LCT)
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- Target: TMEFF2
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-TENB2-mc-vc-PABC-MMAE ADC (ADC-136LZY)
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- Target: TENB2
- Linker: mc-VC-PABC (maleimidocaproyl-valine-citrullinepara-aminobenzyloxycarbonyl)
- Drug: MMAE (monomethyl auristatin E)
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the tomoregulin family of transmembrane proteins. This protein has been shown to function as both an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion. Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding. Additionally, this gene has been found to be hypermethylated in multiple cancer types. Alternative splicing results in multiple transcript variants.
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Excitatory neurons, Inhibitory neurons, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AF22, LHCN-M2)
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