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TMEM37
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- PE-A*02:01/Human PR-1 (VLQELNVTV) MHC Tetramer (MHC-LC010)
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- Class: Class I
- Antigen: PR-1
- Antigen Species: Human
- Peptide: VLQELNVTV
- Conjugate: PE
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- APC-A*02:01/Human PR-1 (VLQELNVTV) MHC Tetramer (MHC-LC011)
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- Class: Class I
- Antigen: PR-1
- Antigen Species: Human
- Peptide: VLQELNVTV
- Conjugate: APC
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- APC-A*02:01/Human PR1 (VLQELNVTV) MHC Tetramer (MHC-CN0329)
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- Class: Class I
- Antigen: PR1
- Antigen Species: Human
- Peptide: VLQELNVTV
- Conjugate: APC
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- PE-A*02:01/Human PR1 (VLQELNVTV) MHC Tetramer (MHC-CN0330)
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- Class: Class I
- Antigen: PR1
- Antigen Species: Human
- Peptide: VLQELNVTV
- Conjugate: PE
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- A*02:01/Human PR-1 (VLQELNVTV) MHC Monomer (MHC-YF229)
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- Class: Class I
- Antigen: PR-1
- Antigen Species: Human
- Peptide: VLQELNVTV
- Conjugate: Biotin
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For Research Use Only. Not For Clinical Use.
PR1 is a human leukocyte antigen (HLA)-A2 restricted peptide that has been targeted successfully in myeloid leukemia with immunotherapy. PR1 is derived from the neutrophil granule proteases proteinase 3 (P3) and neutrophil elastase (NE), which are both found in the tumor microenvironment.
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Proximal tubular cells, Hepatocytes, Distal enterocytes, Muller glia cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (EFO-21, Hep G2, RPTEC TERT1)
Interaction
The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.
Molecular function
Calcium channel, Ion channel, Voltage-gated channel
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