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TMOD2

Anti-TMOD2 Products

Anti-Mouse TMOD2 Immunohistochemistry Kit (VS-0525-XY7339)
- Species Reactivity: Human, Mouse, Rat
- Target: TMOD2
- Application: IHC
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Anti-TMOD2 Immunohistochemistry Kit (VS-0525-XY7338)
- Species Reactivity: Human
- Target: TMOD2
- Application: IHC
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Rabbit Anti-TMOD2 Recombinant Antibody (clone DS3593AB) (MOR-3593)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, ICC, IP
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons, Astrocytes, Oligodendrocyte precursor cells, Oligodendrocytes, Horizontal cells)

Immune cell specificity

Immune cell enhanced (neutrophil)

Cell line specificity

Cell line enhanced (SCLC-21H)

Interaction

Binds to the N-terminus of tropomyosin and to actin.

Molecular function

Actin-binding

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