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TNF

rAbs(268)
Glyco-Abs(16)
Scaffolds(4)
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This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Recombinant Anti-Human TNF Antibody (MOB-1076z)
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, Dot, FuncS
Inquiry
Recombinant Anti-Human TNF Antibody Fab Fragment (MOB-1076z-F(E))
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
ELISA, FacS, FuncS
Inquiry
Recombinant Anti-Human TNF Antibody scFv Fragment (MOB-1076z-S(P))
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
IF, FC, Biosensors, FuncS
Inquiry
Recombinant Anti-human TNF VHH Single Domain Antibody (NABL-051)
Species Reactivity:
Human
Type:
Llama VHH
Application:
WB, ELISA, IHC, FC, FuncS
Inquiry
Anti-Human TNF alpha Therapeutic Antibody (Simponi) (TAB-062)
Derivation:
Human
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
FC, IP, ELISA, Neut, FuncS, IF, ICC
Inquiry
Anti-Human TNF Therapeutic Antibody (Humira) (TAB-010)
Derivation:
Human
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
WB, FC, IP, ELISA, Neut, FuncS, IF
Inquiry
Anti-Human TNF-alpha Therapeutic Antibody (Ozoralizumab) (TAB-138)
Derivation:
Humanized
Species Reactivity:
Human
Type:
VH - VH' - VH
Application:
WB, IP, IF, FuncS, FC, Neut, ELISA
Inquiry
Anti-TNF alpha Therapeutic Antibody (nerelimomab) (TAB-768)
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG1
Application:
FuncS, IF, Neut, ELISA, FC, IP, ICC
Inquiry
Anti-Human TNF Therapeutic Antibody (Remicade) (TAB-006)
Derivation:
Chimeric (mouse/human)
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
IF, IP, Neut, FuncS, ELISA, FC, WB
Inquiry
Anti-Human TNF alpha therapeutic Antibody Fab Fragment (Cimzia) (TAB-034-F(E))
Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
Fab'
Application:
ELISA, FC, IP, FuncS, IF, Neut, IHC
Inquiry
Anti-Human TNF Therapeutic Antibody (Placulumab) (TAB-254)
Derivation:
Human
Species Reactivity:
Human
Type:
[V-kappa]2 - Fc
Application:
Neut, ELISA, IF, IP, FuncS, FC, ICC
Inquiry
Anti-TNFα Therapeutic Antibody (Afelimomab) (TAB-718)
Derivation:
Mouse
Species Reactivity:
Human
Type:
F(ab')2 - G3 - kappa
Application:
Neut, ELISA, IF, IP, FuncS, FC, ICC
Inquiry
Anti-Human TNF Therapeutic Antibody (AVX-470) (TAB-623CL)
Derivation:
Cow
Species Reactivity:
Human
Type:
Antibody
Inquiry
Recombinant Anti-IL17 × Anti-TNF Bispecific Antibody (CrossMab) (CROSS-L017)
Targets:
IL17 & TNF
Type:
CrossMab
Application:
FuncS, Promising therapeutic agent
Inquiry
Recombinant Anti-IL17A × Anti-TNF Bispecific Antibody (TandAb) (TAND-L016)
Targets:
IL17A & TNF
Type:
TandAb
Application:
FuncS, Promising therapeutic agent
Inquiry
Recombinant Anti-IL-17A × Anti-TNF Bispecific Antibody (DVD-Ig) (DVD-L009)
Targets:
IL-17A & TNF
Type:
DVD-Ig
Application:
FuncS, Promising therapeutic agent
Inquiry
Afuco™ Anti-Human TNF ADCC Theraputic Antibody (AVX-470), ADCC Enhanced (AFC-601CL)
Derivation:
Cow
Species Reactivity:
Human
Type:
ADCC enhanced antibody
Inquiry
10-FnIII scaffold protein anti-Human TNFα (SFN-L026)
Scaffold Name:
10-FnIII
Target:
TNFα
Species Reactivity:
Human
Derivation:
mRNA Display
Inquiry
Kunitz domains scaffold protein anti-Human TNFα (SKD-L116)
Scaffold Name:
Kunitz domains
Target:
TNFα
Species Reactivity:
Human
Derivation:
Phage display
Inquiry
Ubiquitin scaffold protein anti-TNFα (SUB-L209)
Scaffold Name:
Ubiquitin
Target:
TNFα
Derivation:
Phage display
Inquiry
Z-domain of protein A scaffold protein anti-Human TNFα (SZA-L241)
Scaffold Name:
Z-domain of protein A
Target:
TNFα
Species Reactivity:
Human
Derivation:
Phage display
Inquiry
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