TNF
Anti-TNF Recombinant Antibody Products
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1, κ
- Application: WB, FC, IP, ELISA, Neut, FuncS, IF
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Fab'
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
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- Target: TNF
- Target Species: Human
- Application: IP, Protein Purification
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- Target: TNF
- Target Species: Human, Cynomolgus, Rhesus
- Application: IP, Protein Purification
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC-P, IF
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Neut, IHC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: FuncS
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: FuncS
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- Derivation: Chimeric
- Species Reactivity: Feline
- Type: Mouse IgG
- Application: ELISA, WB
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
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- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
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- Species Reactivity: Canine, Human
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse IgG2b
- Application: ELISA
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC-P, IF
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Derivation: Rat
- Species Reactivity: Mouse
- Type: Rat IgG1, κ
- Application: IF, FC
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- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG
- Application: IHC-P, WB
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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- Species Reactivity: Human, Mouse, Rat
- Application: WB, IHC
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Neut
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- Species Reactivity: Mouse
- Type: Mouse IgG2c
- Application: ELISA, BLI, Neut
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- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG
- Application: WB, IHC
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- Species Reactivity: Rat
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Rat
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: Neut
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IA
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, IHC, FC
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus, Rhesus
- Type: Humanized IgG
- Application: ELISA, Neut, Block, Inhib, FuncS
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- Species Reactivity: Human, Bovine, Canine, Monkey
- Type: Mouse IgG2a
- Application: FuncS, IA
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: ELISA, BA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, FC, FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human IgG
- Application: Neut, Inhib
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- Species Reactivity: Human
- Type: Human IgG
- Application: Neut, Inhib
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- Species Reactivity: Human
- Type: Human IgG
- Application: Neut, Inhib
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Neut
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: IA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: RIA, ELISA, FuncS
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, Neut
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, Neut
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Neut
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: IA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: RIA, ELISA, FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
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- Species Reactivity: Human
- Type: Mouse Fab, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA, Antagonist
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA, Antagonist
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA, Antagonist
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- Species Reactivity: Mouse
- Type: Camelid VHH
- Application: Antagonist
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- Species Reactivity: Mouse
- Type: Camelid VHH
- Application: Antagonist
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- Species Reactivity: Mouse
- Type: Camelid VHH
- Application: Antagonist
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, IHC, FC, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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- Species Reactivity: Mouse, Rat, Rabbit
- Type: Armenian Hamster IgG
- Application: ELISA, FC, Neut, IP, WB
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- Species Reactivity: Human, Rhesus, Cynomolgus, Baboon
- Type: Mouse IgG1, kappa
- Application: FC
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: ELISA, Neut
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- Antibody Host: Human
- Antibody Reactivity: Human
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- Antibody Host: Mouse
- Antibody Reactivity: Human
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For Research Use Only. Not For Clinical Use.
TNF is a cytokine produced by macrophages, T cells, and other immune cells. It exists in both membrane - bound and soluble forms. TNF binds to two main receptors, TNF receptor 1 (TNFR1) and TNF receptor 2 (TNFR2). TNF has diverse functions, including induction of apoptosis in tumor cells, activation of immune cells, and promotion of inflammation. In inflammation, TNF stimulates the production of other cytokines and chemokines, recruits immune cells to the site of infection or injury, and increases vascular permeability. However, excessive TNF production can lead to tissue damage and is associated with diseases like rheumatoid arthritis and sepsis.