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TNFRSF10C
Loading...Anti-TNFRSF10C Products
- Mouse Anti-TNFRSF10C Recombinant Antibody (clone CBL508) (NEUT-2110CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut
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- AbPlus™ Anti-TNFRSF10C Magnetic Beads (VS-0724-YC1229) (VS-0724-YC1229)
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- Target: TNFRSF10C
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
Protein class
Cancer-related genes, CD markers
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Gastric mucus-secreting cells, granulocytes, Alveolar cells type 2, Alveolar cells type 1, Proximal enterocytes, Endothelial cells)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Group enriched (BEWO, HUVEC TERT2)
Molecular function
Receptor
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