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TNFRSF11B

Anti-TNFRSF11B Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, ICC, IF
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- Species Reactivity: Human
- Application: WB
- Mouse Anti-TNFRSF11B Recombinant Antibody (clone CBL485) (NEUT-2118CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut
- Mouse Anti-TNFRSF11B Recombinant Antibody (clone CBL181) (NEUT-2119CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut, WB
- Mouse Anti-TNFRSF11B Recombinant Antibody (clone 9C1) (MRO-1136-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IF, IHC
- Mouse Anti-TNFRSF11B Recombinant Antibody (clone 9C2) (MRO-1137-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IF, IHC
- Rabbit Anti-TNFRSF11B Polyclonal Antibody (MRO-2102-CN) (MRO-2102-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, ICC, FC
- Mouse Anti-TNFRSF11B Monoclonal Antibody (VS7-0425-WR1014) (VS7-0425-WR1014)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IF, ICC, FC, ELISA
- Mouse Anti-TNFRSF11B Monoclonal Antibody (VS7-0425-WR1015) (VS7-0425-WR1015)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ELISA
- Anti-TNFRSF11B Immunohistochemistry Kit (VS-0525-XY7367)
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- Species Reactivity: Human
- Target: TNFRSF11B
- Application: IHC
- Anti-Human TNFRSF11B Immunohistochemistry Kit (VS-0525-XY7368)
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- Species Reactivity: Human, Porcine
- Target: TNFRSF11B
- Application: IHC
- Anti-Rat TNFRSF11B Immunohistochemistry Kit (VS-0525-XY7369)
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- Species Reactivity: Human, Rat
- Target: TNFRSF11B
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, ICC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Protein class
Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Breast glandular cells, Proximal tubular cells, Collecting duct cells, Ductal cells)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Group enriched (BJ, BJ hTERT+)
Interaction
Homodimer. Interacts with TNFSF10 and TNFSF11.
Molecular function
Receptor
More Types Infomation