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TNFSF4

Engineered Antibody
This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
TNFSF4
Protein class

Cancer-related genes, CD markers, Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Granulosa cells, Macrophages, Astrocytes, monocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (fHDF/TERT166, HHSteC, HUVEC TERT2, LHCN-M2)

Interaction

Homotrimer.

Molecular function

Cytokine

More Types Infomation
More Infomation

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For Research Use Only. Not For Clinical Use.

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