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TPK1
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Protein class
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Microglial cells, Late spermatids, Early spermatids, Excitatory neurons, Inhibitory neurons)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (AN3-CA, CACO-2, EFO-21, TIME)
Interaction
Homodimer.
Molecular function
Kinase, Transferase
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