Loading...
TUBB3
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Pancreatic endocrine cells, Inhibitory neurons, Excitatory neurons, Ductal cells, Gastric mucus-secreting cells, Exocrine glandular cells, Astrocytes)
Immune cell specificity
Immune cell enriched (naive B-cell)
Cell line specificity
Cell line enhanced (A549, SCLC-21H, SH-SY5Y)
Interaction
Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells. Interacts with UNC5C (via cytoplasmic domain); this interaction is decreased by NTN1/Netrin-1 (PubMed:28483977). Interacts with NLRP5/MATER at cytoskeleton microtubules (PubMed:24374158). Interacts with DPYSL5 (PubMed:33894126).
More Types Infomation
- Rabbit Anti-TUBB3 Polyclonal Antibody (MRO-1693-CN) (MRO-1693-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, FC
- Mouse Anti-TUBB3 Recombinant Antibody (clone A8-D10) (MRO-1079-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG2a
- Application: WB, IF, IHC
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P
-
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
- Rabbit Anti-TUBB3 Polyclonal Antibody (MRO-1689-CN) (MRO-1689-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
-
- Species Reactivity: Human, Monkey, Mouse, Rat, Bovine, Porcine
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, ICC, IP
-
- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, FuncS
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, IF
- Rabbit Anti-TUBB3 Polyclonal Antibody (MRO-0224YJ)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, ICC, ELISA
- Rabbit Anti-TUBB3 Recombinant Antibody (clone AFY0043) (MOR-0072-FY)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: ICC, IHC-P, WB
- Rabbit Anti-TUBB3 Polyclonal Antibody (MRO-2068-CN) (MRO-2068-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
- Mouse Anti-TUBB3 Recombinant Antibody (clone 1-B11) (MRO-1617-CN)
-
- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Mouse IgG1
- Application: WB, IF, IHC, FC
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC, IP, IHC
-
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
- Rabbit Anti-TUBB3 Recombinant Antibody (clone CBACN-565) (MRO-1539-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP, FC
- Human Anti-TUBB3 Antibody (clone YC093), mRNA (PABL-411-mRNA)
-
- Species Reactivity: Human
-
- Species Reactivity: Human, Rat, Mouse, Monkey, Dog, Chicken, Hamster, Rabbit, Sheep, Insect, Yeast
- Type: Mouse IgG
- Application: WB, IF, IHC-P
-
- Species Reactivity: Human, Rat, Mouse, Monkey, Dog, Chicken, Hamster, Rabbit, Sheep, Insect, Yeast
- Type: Mouse IgG
- Application: WB, IF, IHC-P
-
- Species Reactivity: Human, Rat, Mouse, Monkey, Dog, Chicken, Hamster, Rabbit, Sheep, Insect, Yeast
- Type: Mouse IgG
- Application: WB, IF, IHC-P
-
- Species Reactivity: Human, Rat, Mouse, Monkey, Dog, Chicken, Hamster, Rabbit, Sheep, Insect, Yeast
- Type: Mouse IgG
- Application: WB, IF, IHC-P
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.