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Thsd1

The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Protein class

Disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Endothelial cells, Astrocytes, Adipocytes, Spermatocytes, Microglial cells, Hepatic stellate cells, Basal respiratory cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (fHDF/TERT166, HBEC3-KT, hTCEpi, hTERT-HME1, HUVEC TERT2, LHCN-M2)

Interaction

Part of a complex composed of THSD1, PTK2/FAK1, TLN1 and VCL (PubMed:29069646). Interacts with TLN1 (PubMed:27895300, PubMed:29069646).

More Types Infomation

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