In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain, and CD3 molecules together comprise the TCR complex.
TACSTD2 (Tumor Associated Calcium Signal Transducer 2) is a Protein Coding gene. Diseases associated with TACSTD2 include Corneal Dystrophy, Gelatinous Drop-Like and Lattice Corneal Dystrophy. Among its related pathways are Adhesion and Ca, cAMP and Lipid Signaling. An important paralog of this gene is EPCAM.