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UL123
It plays an important role in transactivating viral early genes as well as activating its own promoter. Targets and disrupts host PML/nuclear domain 10 (ND10). Promotes efficient viral growth by interacting with and directing host SP100 to degradation, leading to enhanced acetylation level of histones. In addition, functions in counteracting the host innate antiviral response. Inhibits the type I interferon pathway by directly interacting with and sequestrating host STAT2. Alters host cell cycle progression, probably through its interaction with host E2F1 or RB1 that overcomes the RB1-mediated repression of E2F-responsive promoters.
- A*24:02/CMV IE-1 (AYAQKIFKI) MHC Monomer (MHC-YF301)
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- Class: Class I
- Antigen: IE-1
- Antigen Species: CMV
- Peptide: AYAQKIFKI
- Conjugate: Biotin
- Recombinant Human Anti-UL123 Soluble TCR (2A) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2507)
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- Species Reactivity: HCMV
- Epitope: ELRRKMMYM
- MHC: HLA-B8
- Recombinant Human Anti-UL123 Soluble TCR (13) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2506)
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- Species Reactivity: HCMV
- Epitope: LSEFCRVLCCYVLEE
- MHC: HLA class I
- Recombinant Human Anti-UL123 Soluble TCR (IE.VLE) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2539)
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- Species Reactivity: HCMV
- Epitope: VLEETSVML
- MHC: HLA-A*02:01
- Recombinant Human Anti-UL123 Soluble TCR (IE.QIK) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2538)
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- Species Reactivity: HCMV
- Epitope: QIKVRVKMV
- MHC: HLA-B*08:01
- Recombinant Human Anti-UL123 Soluble TCR (CRV7) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2537)
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- Species Reactivity: HCMV
- Epitope: CRVLCCYVL
- MHC: HLA-C*07:02
- Human Anti-UL123 Recombinant Soluble TCR (clone CRV1-11) (scTCR-1231YC-S(P))
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- Species Reactivity: HCMV
- Epitope: CRVLCCYVL
- MHC: HLA-C*07:02
- Human Anti-UL123 Recombinant Soluble TCR (clone CRV1-10) (scTCR-1230YC-S(P))
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- Species Reactivity: HCMV
- Epitope: CRVLCCYVL
- MHC: HLA-C*07:02
- Human Anti-UL123 Recombinant Soluble TCR (clone CRV1-1) (scTCR-1229YC-S(P))
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- Species Reactivity: HCMV
- Epitope: CRVLCCYVL
- MHC: HLA-C*07:02
- Human Anti-UL123 Recombinant Soluble TCR (clone 3I) (scTCR-1228YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 3H) (scTCR-1227YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 3G) (scTCR-1226YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 3F) (scTCR-1225YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 3E) (scTCR-1224YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 3D) (scTCR-1223YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 3C) (scTCR-1222YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 3B) (scTCR-1221YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 3A) (scTCR-1220YC-S(P))
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- Species Reactivity: HCMV
- Epitope: QIKVRVDMV
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 2B) (scTCR-1219YC-S(P))
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- Species Reactivity: HCMV
- Epitope: ELRRKMMYM
- MHC: HLA-B8
- Human Anti-UL123 Recombinant Soluble TCR (clone 2A) (scTCR-1218YC-S(P))
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- Species Reactivity: HCMV
- Epitope: ELRRKMMYM
- MHC: HLA-B8
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For Research Use Only. Not For Clinical Use.