WIPF1

Formats

Anti-WIPF1 Recombinant Antibody Products

Mouse Anti-WIPF1 Recombinant Antibody (MOB-3675z) (MOB-3675z)
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC-P, ELISA
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Recombinant Anti-Human WIPF1 Antibody Fab Fragment (MOB-3675z-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: RIA, WB, FuncS
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Recombinant Anti-Human WIPF1 Antibody scFv Fragment (MOB-3675z-S(P))
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FC, FuncS
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For Research Use Only. Not For Clinical Use.

Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus.

Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (NK-cells, Oligodendrocytes, T-cells, monocytes, dendritic cells, Plasma cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Daudi, Karpas-707, U-266/70)

Interaction

Binds to WAS, profilin and actin. Binds to WASL (By similarity). Interacts with DBNL. Interacts with FNBP1L (via the SH3 domain) (PubMed:19798448).