Disease related genes, Human disease related genes
Secreted
Group enriched (Late spermatids, Basal keratinocytes, Early spermatids, Suprabasal keratinocytes)
Not detected in immune cells
Cell line enhanced (AF22, U-698)
Forms a soluble 1:1 complex with AFM; this prevents oligomerization and is required for prolonged biological activity (PubMed:26902720). The complex with AFM may represent the physiological form in body fluids (PubMed:26902720). Interacts with PORCN. Interacts with WLS (By similarity).
Developmental protein
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For Research Use Only. Not For Clinical Use.