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WT1
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
Hi-Affi™ Recombinant Rabbit Anti-WT1 Monoclonal Antibody (DS3886AB) (MOR-3886)
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP
Afuco™ Anti-Human WT1 ADCC Theraputic Antibody (ESKM), ADCC Enhanced (AFC-643CL)
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
Anti-Human WT1 Therapeutic Antibody (ESKM) (TAB-670CL)
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- Derivation: Human
- Species Reactivity: Human
- Type: Antibody
Recombinant Rabbit Anti-WT1 Monoclonal Antibody (CBACN-584) (MRO-1597-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
Human Anti-WT1 Antibody (Aali) (CBMAB-117CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, WB, FC, FuncS
Recombinant Mouse Anti-Human Wilms Tumor 1 Antibody (clone 7G-H3) (MOB-0344MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC
Recombinant Human Anti-WT1 Antibody (ESK1) (PABL-359)
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, FuncS
Recombinant Anti-Human WT1 Antibody (MOB-1458z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FC, FuncS
Recombinant Human Anti-WT1 Antibody scFv Fragment (ESK1) (PSBL-359)
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, FuncS
Recombinant Anti-Human WT1 Antibody scFv Fragment (MOB-1458z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
Recombinant Human Anti-WT1 Antibody Fab Fragment (ESK1) (PFBL-359)
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, FuncS
Recombinant Anti-Human WT1 Antibody Fab Fragment (MOB-1458z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, FACS, FuncS
Anti-WT1 immunotoxin 6F-H2 (IgG)-RTA (AGTO-G065R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
BV421-HLA-A2/Human WT1 (YMFPNAPYL) MHC Tetramer (MHC-LC1573)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: YMFPNAPYL
- Conjugate: BV421
APC-HLA-A2/Human WT1 (YMFPNAPYL) MHC Tetramer (MHC-LC1572)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: YMFPNAPYL
- Conjugate: APC
PE-HLA-A2/Human WT1 (YMFPNAPYL) MHC Tetramer (MHC-LC1571)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: YMFPNAPYL
- Conjugate: PE
A*0201/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-LC768)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
H-2Db/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-LC200)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
H-2Db/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-LC199)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
A*02:01/Human WT1 (VLDFAPPGA) MHC Tetramer (MHC-LC196)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: VLDFAPPGA
- Conjugate: APC
A*02:01/Human WT1 (VLDFAPPGA) MHC Tetramer (MHC-LC195)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: VLDFAPPGA
- Conjugate: PE
A*02:01/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-LC114)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
A*02:01/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-LC113)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
A*24:02/Human WT1(mutant) (CYTWNQMNL) MHC Tetramer (MHC-LC112)
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- Class: Class I
- Target: WT1(mutant)
- Specificity: Human
- Peptide: CYTWNQMNL
- Conjugate: APC
A*24:02/Human WT1(mutant) (CYTWNQMNL) MHC Tetramer (MHC-LC111)
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- Class: Class I
- Target: WT1(mutant)
- Specificity: Human
- Peptide: CYTWNQMNL
- Conjugate: PE
A*02:01/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-LC093)
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- Class: Class I
- Target: WT-1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: BV421
A*24:02/Human Modified WT1 (CYTWNQMNL) MHC Tetramer (MHC-LC092)
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- Class: Class I
- Target: Modified WT1
- Specificity: Human
- Peptide: CYTWNQMNL
- Conjugate: BV421
B*27:05/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-CN1408)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: Unconjugated
FITC-B*27:05/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-CN1407)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: FITC
APC-B*27:05/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-CN1406)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
PE-B*27:05/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-CN1405)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
A*02:01/Human WT1 (SLGEQQYSV) MHC Tetramer (MHC-CN1404)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: SLGEQQYSV
- Conjugate: Unconjugated
FITC-A*02:01/Human WT1 (SLGEQQYSV) MHC Tetramer (MHC-CN1403)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: SLGEQQYSV
- Conjugate: FITC
APC-A*02:01/Human WT1 (SLGEQQYSV) MHC Tetramer (MHC-CN1402)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: SLGEQQYSV
- Conjugate: APC
PE-A*02:01/Human WT1 (SLGEQQYSV) MHC Tetramer (MHC-CN1401)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: SLGEQQYSV
- Conjugate: PE
A*01:01/Human WT1 (TSEKRPFMCAY) MHC Tetramer (MHC-CN1400)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: TSEKRPFMCAY
- Conjugate: Unconjugated
FITC-A*01:01/Human WT1 (TSEKRPFMCAY) MHC Tetramer (MHC-CN1399)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: TSEKRPFMCAY
- Conjugate: FITC
APC-A*01:01/Human WT1 (TSEKRPFMCAY) MHC Tetramer (MHC-CN1398)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: TSEKRPFMCAY
- Conjugate: APC
PE-A*01:01/Human WT1 (TSEKRPFMCAY) MHC Tetramer (MHC-CN1397)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: TSEKRPFMCAY
- Conjugate: PE
H-2Db/Human WT1 (CMTWNQMNL) MHC Tetramer (MHC-CN1396)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: CMTWNQMNL
- Conjugate: Unconjugated
FITC-H-2Db/Human WT1 (CMTWNQMNL) MHC Tetramer (MHC-CN1395)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: CMTWNQMNL
- Conjugate: FITC
APC-H-2Db/Human WT1 (CMTWNQMNL) MHC Tetramer (MHC-CN1394)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: CMTWNQMNL
- Conjugate: APC
PE-H-2Db/Human WT1 (CMTWNQMNL) MHC Tetramer (MHC-CN1393)
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- Class: Class I
- Target: WT1
- Specificity: Human
- Peptide: CMTWNQMNL
- Conjugate: PE
PE-A*02:01/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0242)
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- Class: Class I
- Target: WT-1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
PE-A*02:01_Mut/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0241)
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- Class: Class I
- Target: WT-1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
PE-H-2Db/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0240)
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- Class: Class I
- Target: WT-1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
APC-A*02:01/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0239)
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- Class: Class I
- Target: WT-1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
APC-A*02:01_Mut/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0238)
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- Class: Class I
- Target: WT-1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
APC-H-2Db/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0237)
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- Class: Class I
- Target: WT-1
- Specificity: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
PE-A*02:01/Human WT-1 (CMTWNQMNL) MHC Tetramer (MHC-CN0034)
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- Class: Class I
- Target: WT-1
- Specificity: Human
- Peptide: CMTWNQMNL
- Conjugate: PE
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