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WT1
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
A*02:01/Human WT-1 (RMFPNAPYL) MHC Pentamer (MHC-YF780)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: Unlabeled, Biotin, R-PE, APC
H-2Db/Human WT1 (CMTWNQMNL) MHC Pentamer (MHC-YF779)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: CMTWNQMNL
- Conjugate: Unlabeled, Biotin, R-PE, APC
PE-A*02:01/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0242)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
PE-A*02:01_Mut/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0241)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
PE-H-2Db/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0240)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
APC-A*02:01/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0239)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
APC-A*02:01_Mut/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0238)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
APC-H-2Db/Human WT-1 (RMFPNAPYL) MHC Tetramer (MHC-CN0237)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
BV421-HLA-A2/Human WT1 (YMFPNAPYL) MHC Tetramer (MHC-LC1573)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: YMFPNAPYL
- Conjugate: BV421
PE-HLA-A2/Human WT1 (YMFPNAPYL) MHC Tetramer (MHC-LC1571)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: YMFPNAPYL
- Conjugate: PE
A*02:01/Human WT-1 (SLGEQQYSV) MHC Pentamer (MHC-YF781)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: SLGEQQYSV
- Conjugate: Unlabeled, Biotin, R-PE, APC
B*27:05/Human WT-1 (RMFPNAPYL) MHC Pentamer (MHC-YF782)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: Unlabeled, Biotin, R-PE, APC
H-2Db/Human WT-1 (RMFPNAPYL) MHC Pentamer (MHC-YF783)
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- Class: Class I
- Antigen: WT-1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: Unlabeled, Biotin, R-PE, APC
A*02:01/Human WT1 (VLDFAPPGA) MHC Tetramer (MHC-LC195)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: VLDFAPPGA
- Conjugate: PE
A*02:01/Human WT1 (VLDFAPPGA) MHC Tetramer (MHC-LC196)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: VLDFAPPGA
- Conjugate: APC
H-2Db/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-LC199)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: PE
H-2Db/Human WT1 (RMFPNAPYL) MHC Tetramer (MHC-LC200)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: RMFPNAPYL
- Conjugate: APC
PE-H-2Db/Human WT1 (CMTWNQMNL) MHC Tetramer (MHC-CN1393)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: CMTWNQMNL
- Conjugate: PE
APC-H-2Db/Human WT1 (CMTWNQMNL) MHC Tetramer (MHC-CN1394)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: CMTWNQMNL
- Conjugate: APC
FITC-H-2Db/Human WT1 (CMTWNQMNL) MHC Tetramer (MHC-CN1395)
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- Class: Class I
- Antigen: WT1
- Antigen Species: Human
- Peptide: CMTWNQMNL
- Conjugate: FITC
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