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ZBED1
Binds to 5-TGTCG[CT]GA[CT]A-3 DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (BEWO)
Interaction
Homodimer and homomultimer (PubMed:17209048). Homodimerization is necessary for protein nuclear localization and DNA binding (PubMed:17209048). Interacts with KPNB1; required for nuclear import of ZBED1/hDREF (PubMed:17209048). Interacts with CHD3/Mi2-alpha (PubMed:27068747). Interacts with SUMO1 (PubMed:27068747). Interacts with UBE2I/UBC9 (PubMed:27068747). (Microbial infection) Interacts (via C-terminus) with human adenovirus early E1A protein (via C-terminus); the interaction is direct.
Molecular function
DNA-binding, Transferase
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
- Recombinant Mouse Anti-Human ZBED1 Antibody (MOB-2076MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.