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ZNF81
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause mental retardation X-linked type 45 (MRX45). [provided by RefSeq, May 2010]
Protein class
Disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Astrocytes, Oligodendrocyte precursor cells, Inhibitory neurons, Excitatory neurons)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (U-266/84)
Molecular function
DNA-binding
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